ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases
In gut epithelium, IL-22 transmits signals through STAT3 phosphorylation (pSTAT3) which provides intestinal immunity.Many components in the IL-22-pSTAT3 pathway have been identified as risk factors for inflammatory bowel viqua-f4 disease (IBD) and some of them are considered as promising therapeutic targets.However, new perspectives are still neede